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KMID : 0367320030140010064
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Journal of the Korean Academy of Child and Adolescent Psychiatry
2003 Volume.14 No. 1 p.64 ~ p.80
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THERAPEUTIC APPROACHES FOR TREATMENT RESISTANT OBSESSIVE-COMPULSIVE DISORDER IN CHILDREN AND ADOLESCENTS
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Suh Hyun-Ju
Kim Bung-Nyun
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Abstract
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Although obsessive-compulsive disorder (OCD) affects children, adolescents, and adults whether its juvenile (dhild and adolescent) and adult forms are different subtype of a disorder remains unknown. But there are increasing findings that suggest that juvenile OCD may be unique subtype of the disorder.
One proposed subtype is the childhood OCD associated with high comorbidity of tic disorder and increased familial loading for OCD or tic disorder. The other proposed subtype is the childhood OCD and/or tic disorder occuring in association with streptococcal infection (PANDAS). These two subtypes of OCD are unlikely to respond to SSRI due to possible different pathphysiological mechanism So this paper reviews the characteristics of OCD and therapeutic approaches for treatment resistant OCD in childhood and adolescence.
Considering the likely heterogeneity of OCD, the possibility that juvenild OCD may be a variant of the disorder can have important clinical and scientific impl´cations because it may further our understanding of this disorder, its etiology, and perhaps its treatment.
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KEYWORD
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Obsessive-compulsive disorder, Childhood, subtype, Treatment resistant
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